Trustmed Lifecare

Amoxicillin and Potassium Clavulanate Tablets IP 625 mg is a combination antibiotic used to treat various bacterial infections.  Each tablet contains 500 mg of amoxicillin (equivalent to amoxicillin trihydrate) and 125 mg of potassium clavulanate (equivalent to clavulanic acid).  The amoxicillin component works by inhibiting bacterial cell wall synthesis, while clavulanic acid acts as a beta-lactamase inhibitor, preventing certain bacteria from breaking down amoxicillin and enhancing its effectiveness against resistant strains. 

Key Uses

• Respiratory tract infections: Acute bacterial sinusitis, acute otitis media, acute exacerbations of chronic bronchitis, community-acquired pneumonia. 

• Urinary tract infections: Cystitis, pyelonephritis. 

• Skin and soft tissue infections: Cellulitis, animal bites, severe dental abscesses with spreading. 

• Bone and joint infections: Osteomyelitis. 

• Other infections: Intra-abdominal sepsis, puerperal sepsis, septic abortion.

Dosage and Administration

• Adults and children ≥ 40 kg: One tablet three times daily (500 mg/125 mg every 8 hours). 

• Children < 40 kg: Dose based on body weight (20–60 mg amoxicillin/5–15 mg clavulanic acid per kg per day), divided into three doses. Tablets are not suitable for children weighing less than 25 kg due to inability to divide them.