Trustmed Lifecare

Levofloxacin 750 mg Tablets IP are a prescription antibiotic belonging to the fluoroquinolone class, used to treat various bacterial infections in adults and children over 6 months of age.  Each tablet contains Levofloxacin Hemihydrate equivalent to 750 mg of Levofloxacin, the active ingredient.  It works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication and transcription, leading to bacterial cell death. 

Key Uses

• Respiratory tract infections: Community-acquired pneumonia, acute bacterial exacerbation of chronic bronchitis, acute bacterial sinusitis. 

• Skin and soft tissue infections: Complicated and uncomplicated infections. 

• Urinary tract infections: Complicated UTIs, acute pyelonephritis. 

• Other infections: Nosocomial pneumonia, chronic bacterial prostatitis, inhalational anthrax (post-exposure), and plague. 

Dosage and Administration

• Adults: Typically 750 mg once daily for 5 to 14 days, depending on the infection type.

  • Example: 5 days for acute pyelonephritis or acute bacterial sinusitis; 7–14 days for complicated skin infections or pneumonia.

Lquin 500 Tablet is a prescription antibiotic medication containing Levofloxacin (500 mg), belonging to the fluoroquinolone class of antibiotics.  It is used to treat a wide range of bacterial infections, including:

• Respiratory tract infections (e.g., pneumonia, bronchitis)

• Urinary tract infections (UTIs), including bladder and kidney infections

• Skin and soft tissue infections

• Prostatitis (chronic bacterial)

• Infections of the sinuses and gastrointestinal tract

• Complicated infections such as acute pyelonephritis and inhalation anthrax 

The tablet works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication, repair, and recombination.  This action prevents bacterial cell division and leads to bacterial cell death. 

Tinidazole 500 mg tablets are oral medications used to treat various infections caused by protozoa and anaerobic bacteria.  Each tablet contains 500 mg of tinidazole, a synthetic antiprotozoal and antibacterial agent.  The tablets are typically film-coated, off-white to pale yellow, modified oval, and scored for easy splitting. 

Key Uses

• Trichomoniasis: A single 2 g dose (four 500 mg tablets) is recommended for both male and female patients; concurrent treatment of sexual partners is advised. 

• Bacterial Vaginosis (BV): A 2 g dose daily for 2 days or a 1 g dose daily for 5 days is effective. Some protocols combine it with boric acid and probiotics. 

• Giardiasis: A single 2 g dose (four tablets) is used for intestinal infection. 

• Amoebiasis:

  • Intestinal: 2 g daily for 2–3 days.

  • Liver abscess: 1.5–2 g daily for 3–6 days, depending on severity.

• Anaerobic Infections: Initial 2 g dose on day 1, followed by 1 g daily for 5–6 days. Used for peritonitis, sepsis, pneumonia, post-operative infections, and gynecological infections. 

• H. pylori Eradication: 500 mg twice daily for 7 days, combined with omeprazole and clarithromycin. 

• Post-operative Infection Prophylaxis: A single 2 g dose 12 hours before surgery. 

Dosage & Administration

• Take with food to reduce gastrointestinal side effects. 

• Do not crush or chew unless instructed by a pharmacist.

• Avoid alcohol during treatment and for at least 72 hours after stopping to prevent a disulfiram-like reaction (flushing, nausea, vomiting, tachycardia). 

Important Precautions

• Contraindications: Hypersensitivity to tinidazole or other nitroimidazoles, blood dyscrasias, or organic neurological disorders.

• Pregnancy & Breastfeeding: Contraindicated in the first trimester; use cautiously in later stages. Avoid breastfeeding for at least 3 days after discontinuation.

• Neurological Effects: Dizziness, vertigo, or ataxia may occur; discontinue if symptoms develop.

• Renal Impairment: Dose adjustment generally not needed, but patients on hemodialysis may require additional doses.